Leukoaraiosis and risk of intracranial hemorrhage and outcome after stroke thrombolysis
نویسندگان
چکیده
منابع مشابه
Leukoaraiosis, intracerebral hemorrhage, and functional outcome after acute stroke thrombolysis
OBJECTIVE To perform a systematic review and pooled meta-analysis of published studies to assess whether the presence of leukoaraiosis on neuroimaging before treatment with thrombolysis (IV or intra-arterial) is associated with an increased risk of symptomatic intracerebral hemorrhage (sICH) or poor functional outcome. METHODS We included studies of patients with acute ischemic stroke, treate...
متن کاملLeukoaraiosis, Cerebral Hemorrhage, and Outcome After Intravenous Thrombolysis for Acute Ischemic Stroke
The effectiveness and benefit of intravenous (IV) thrombolysis using recombinant tissue-type plasminogen activator (r-tPA) within 4.5 hours for acute ischemic stroke (AIS) have been clearly demonstrated. However, early symptomatic intracranial hemorrhage (sICH) remains the most serious complication after IV thrombolysis. Given the increasing number of patients eligible for IV thrombolysis, espe...
متن کاملLeukoaraiosis, Cerebral Hemorrhage, and Outcome After Intravenous Thrombolysis for Acute Ischemic Stroke: A Meta-Analysis (v1).
BACKGROUND AND PURPOSE We performed a meta-analysis to assess whether leukoaraiosis on brain computed tomographic scans of acute ischemic stroke patients treated with intravenous thrombolysis is associated with an increased risk of symptomatic intracerebral hemorrhage (sICH) or poor functional outcome at 3 to 6 months after stroke, or both. METHODS We searched PubMed and pooled relevant data ...
متن کاملLeukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke.
BACKGROUND AND PURPOSE The aim of the study was to evaluate whether leukoaraiosis (LA) is a risk factor for symptomatic intracerebral hemorrhage (sICH) in patients treated with thrombolysis for acute stroke. METHODS In this retrospective, multicenter analysis, we evaluated data from acute anterior circulation stroke patients (n=449; <6 hours after symptom onset) treated with thrombolysis. All...
متن کاملPrior statin use, intracranial hemorrhage, and outcome after intra-arterial thrombolysis for acute ischemic stroke.
BACKGROUND AND PURPOSE There are only limited data on whether prior statin use and/or cholesterol levels are associated with intracranial hemorrhage (ICH) and outcome after intra-arterial thrombolysis. The purpose of this study was to evaluate the association of statin pretreatment and cholesterol levels with the overall frequency of ICH, the frequency of symptomatic ICH, and clinical outcome a...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0196505